Which statement is not applicable for Cryoprecipitate?

• A. Pooled at room temperature and expires within 5 hours in open systems
• B. Rich in fibrinogen and factor XIII
• C. Stored frozen until use
• D. Contains factor VIII and von Willebrand factor

Answer: (A)

Cryoprecipitate is a plasma-derived product prepared from thawed plasma and then frozen for storage. It is specifically rich in fibrinogen and factor XIII, and it also contains factor VIII and von Willebrand factor, making it useful for fibrinogen replacement and related coagulopathies. Handling and storage are designed to preserve these factors: the product is kept frozen until use and is thawed just before transfusion, rather than being pooled or stored at room temperature in open systems. Therefore, the statement that it is pooled at room temperature and expires within 5 hours in open systems is not applicable. The other points—being rich in fibrinogen and factor XIII, and containing factor VIII and von Willebrand factor, and being stored frozen until use—are accurate.